de brianb profile

Recent Activity

• 01:08: posted High-Efficiency Microarray Printer Using Fused-Silica Capillary Tube Printing Pins

• 23:26: posted Assessment of serum proteomics to detect large colon adenomas.
• 04:00: posted Cancer screening: a mathematical model relating secreted blood biomarker levels to tumor sizes.

• 01:13: posted Increasing information from shotgun proteomic data by accounting for misassigned precursor ion masses

• 02:21: posted Ten Commandments: Lessons from the Enzymology of DNA Replication
• 02:05: posted A Quantitative Proteomic Approach for Identification of Potential Biomarkers in Hepatocellular Carcinoma
• 01:58: posted Cell surface proteomics identifies molecules functionally linked to tumor cell intravasation

• 23:32: posted TandTRAQ: an open-source tool for integrated protein identification and quantitation.
• 23:31: posted Calibrating E-values for MS2 database search methods
• 23:30: posted Comparison of Mascot and X!Tandem Performance for Low and High Accuracy Mass Spectrometry and the Development of an Adjusted Mascot Threshold
• 23:23: posted Detection of co-eluted peptides using database search methods
• 23:19: posted A robust linear regression based algorithm for automated evaluation of peptide identifications from shotgun proteomics by use of reversed-phase liquid chromatography retention time
• 22:39: posted X!!Tandem, an Improved Method for Running X!Tandem in Parallel on Collections of Commodity Computers
• 19:42: posted Spectral dictionaries: Integrating de novo peptide sequencing with database search of tandem mass spectra

• 22:57: posted Precursor-Ion Mass Re-Estimation Improves Peptide Identification on Hybrid Instruments
• 22:57: posted Immobilized Metal Affinity Chromatography Revisited: pH/Acid Control toward High Selectivity in Phosphoproteomics
• 22:53: posted Quantitative analysis of HER2-mediated effects on HER2 and epidermal growth factor receptor endocytosis: distribution of homo- and heterodimers depends on relative HER2 levels.
• 22:51: posted Modeling the effects of HER/ErbB1-3 coexpression on receptor dimerization and biological response.
• 22:50: posted Expression of p95HER2, a Truncated Form of the HER2 Receptor, and Response to Anti-HER2 Therapies in Breast Cancer
• 22:49: posted Rationale for a phase II trial of pertuzumab, a HER-2 dimerization inhibitor, in patients with non-small cell lung cancer.
• 22:46: posted Transphosphorylation of kinase-dead HER3 and breast cancer progression: a new standpoint or an old concept revisited?
• 22:45: posted Mechanism of action of anti-HER2 monoclonal antibodies: scientific update on trastuzumab and 2C4.
• 22:38: posted ZD1839, a specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, induces the formation of inactive EGFR/HER2 and EGFR/HER3 heterodimers and prevents heregulin signaling in HER2-overexpressing breast cancer cells.
• 22:35: posted 2C4, a monoclonal antibody against HER2, disrupts the HER kinase signaling pathway and inhibits ovarian carcinoma cell growth.
• 22:33: posted Trastuzumab (herceptin), a humanized anti-Her2 receptor monoclonal antibody, inhibits basal and activated Her2 ectodomain cleavage in breast cancer cells.
• 22:09: posted Peptide vaccines of the HER-2/neu dimerization loop are effective in inhibiting mammary tumor growth in vivo.
• 22:06: posted Differential regulation of tumor angiogenesis by distinct ErbB homo- and heterodimers.
• 21:56: posted DIABLA: A New Screening Method for the Discovery of Protein Targets

• 20:52: posted A General Definition and Nomenclature for Alternative Splicing Events
• 15:44: posted Nonlinear Fitting Method for Determining Local False Discovery Rates from Decoy Database Searches

• 23:10: posted Novel polyamine coating providing non-covalent deactivation and reversed electroosmotic flow of fused-silica capillaries for capillary electrophoresis
• 23:09: posted A polyamine coating for enhanced capillary electrophoresis-electrospray ionization-mass spectrometry of proteins and peptides
• 22:58: posted A simplified multidimensional approach for analysis of complex biological samples: on-line LC-CE-MS
• 22:51: posted Assessing the Dynamic Range and Peak Capacity of Nanoflow LC−FAIMS−MS on an Ion Trap Mass Spectrometer for Proteomics
• 22:34: posted Fully Integrated Glass Microfluidic Device for Performing High-Efficiency Capillary Electrophoresis and Electrospray Ionization Mass Spectrometry
• 22:18: posted Identification of c-Src Tyrosine Kinase Substrates Using Mass Spectrometry and Peptide Microarrays
• 05:18: posted Interlaboratory Performance of a Microarray-Based Gene Expression Test to Determine Tissue of Origin in Poorly Differentiated and Undifferentiated Cancers

• 05:31: posted PhosphoPOINT: a comprehensive human kinase interactome and phospho-protein database
• 05:30: posted Gain and loss of phosphorylation sites in human cancer

• 15:16: posted A quantitative atlas of mitotic phosphorylation.
• 15:07: posted A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology
• 15:01: posted Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity.
• 14:58: posted Systems biology: On the cell cycle and its switches
• 14:57: posted A portrait of tissue phosphoprotein stability in the clinical tissue procurement process.
• 14:56: posted The impact of microRNAs on protein output
• 14:51: posted The Ser/Thr/Tyr phosphoproteome of Lactococcus lactis IL1403 reveals multiply phosphorylated proteins.
• 14:48: posted Practical Implementation of 2D HPLC Scheme with Accurate Peptide Retention Prediction in Both Dimensions for High-Throughput Bottom-Up Proteomics
• 14:47: posted Rapid Sample Processing for LC-MS-Based Quantitative Proteomics Using High Intensity Focused Ultrasound

• 15:08: posted Targeted Online Liquid Chromatography Electron Capture Dissociation Mass Spectrometry for the Localization of Sites of in Vivo Phosphorylation in Human Sprouty2