de dchughes profile

Recent Activity

• 14:02: posted Phylogenetic Signal in the Eukaryotic Tree of Life
• 13:36: posted The amphioxus genome illuminates vertebrate origins and cephalochordate biology
• 13:36: posted Extensive variation between inbred mouse strains due to endogenous L1 retrotransposition
• 13:33: posted A protocol for constructing gene targeting vectors: generating knockout mice for the cadherin family and beyond
• 13:12: posted Translation from nonautonomous type IAP retrotransposon is a critical determinant of transposition activity: Implication for retrotransposon-mediated genome evolution
• 13:02: posted The new paradigm of flow cell sequencing
• 13:01: posted Identification and analysis of ancestral hominoid transcriptome inferred from cross-species transcript and processed pseudogene comparisons
• 12:52: posted Two strategies for gene regulation by promoter nucleosomes
• 12:49: posted The biological effects of simple tandem repeats: Lessons from the repeat expansion diseases
• 12:45: posted The mouse A/HeJ Y chromosome: Another good Y gone bad
• 12:34: posted Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5' UTR as in the 3' UTR.
• 12:30: posted A rapid micro chromatin immunoprecipitation assay (ChIP)
• 12:26: posted Production of neurons, astrocytes and oligodendrocytes from mammalian CNS stem cells

• 15:00: posted Endosomal trafficking of Src tyrosine kinase
• 14:58: posted The meaning of nonsense
• 14:10: posted Growth arrest specific protein 6/Axl signaling in human inflammatory renal diseases.

• 13:43: posted RPGR is mutated in patients with a complex X linked phenotype combining primary ciliary dyskinesia and retinitis pigmentosa.
• 13:42: posted Overexpression of RPGR Leads to Male Infertility in Mice Due to Defects in Flagellar Assembly.
• 13:28: posted Synaptopodin-deficient mice lack a spine apparatus and show deficits in synaptic plasticity.
• 13:26: posted Dendritic spines and long-term plasticity
• 11:57: posted A Phylogenomic Study of Birds Reveals Their Evolutionary History
• 11:55: posted Proliferating Cells Express mRNAs with Shortened 3' Untranslated Regions and Fewer MicroRNA Target Sites
• 11:53: posted CELL BIOLOGY: Arrestin' Movement in Cilia.
• 11:49: posted A novel gene that encodes a protein with a putative src homology 3 domain is a candidate gene for familial juvenile nephronophthisis.
• 11:47: posted BIOCHEMISTRY: How Do Proteins Interact?
• 11:25: posted A novel gene encoding an SH3 domain protein is mutated in nephronophthisis type 1.
• 11:16: posted Genomic analysis of mouse retinal development.

• 16:00: posted Polymorphisms in the CNTF and CNTF receptor genes are associated with muscle strength in men and women.
• 15:57: posted Structural and functional abnormalities of retinal ribbon synapses due to Cacna2d4 mutation.
• 13:12: posted BBC NEWS | England | Kent | Baby girl born after bus adverts
• 12:09: posted VEGFR-3 expression is restricted to blood and lymphatic vessels in solid tumors.
• 12:04: posted Catechol-o-methyltransferase gene polymorphism is associated with skeletal muscle properties in older women alone and together with physical activity.

• 17:03: posted Mouse segmental duplication and copy number variation
• 12:36: posted The Platypus Genome Unraveled
• 11:06: posted Evolution of Mammals and Their Gut Microbes
• 11:00: posted The human retinitis pigmentosa GTPase regulator gene variant database.

• 14:24: posted Mutations in the gene coding for guanylate cyclase-activating protein 2 (GUCA1B gene) in patients with autosomal dominant retinal dystrophies.
• 14:15: posted Mutation in the auxiliary calcium-channel subunit CACNA2D4 causes autosomal recessive cone dystrophy.

• 15:49: posted Vasopressin V2 receptor expression along rat, mouse, and human renal epithelia with focus on TAL.

• 16:41: posted Identification of novel mutations in X-linked retinitis pigmentosa families and implications for diagnostic testing.

• 13:37: posted Tuning in to the signals: noncoding sequence conservation in vertebrate genomes
• 12:21: posted Post-transcriptional control of animal histone gene expression-not so different after all...

• 16:26: posted Species-specific subcellular localization of RPGR and RPGRIP isoforms: implications for the phenotypic variability of congenital retinopathies among species.
• 16:17: posted Identification of mutations in the AIPL1, CRB1, GUCY2D, RPE65, and RPGRIP1 genes in patients with juvenile retinitis pigmentosa.
• 14:18: posted A retinitis pigmentosa GTPase regulator (RPGR)- deficient mouse model for X-linked retinitis pigmentosa (RP3)

• 16:47: posted Oocytes in Newborn MRL Mouse Testes.
• 15:29: posted Retinoic acid in development: towards an integrated view
• 15:27: posted The art and design of genetic screens: RNA interference.
• 13:45: posted Psychiatric genetics: progress amid controversy
• 10:04: posted Zona pellucida glycoproteins.

• 12:53: posted Patterning the cranial neural crest: Hinbrain segmentation and hox gene plasticity
• 11:34: posted Identification and characterization of a novel RPGR isoform in human retina.
• 11:30: posted RPGR transcription studies in mouse and human tissues reveal a retina-specific isoform that is disrupted in a patient with X-linked retinitis pigmentosa.
• 11:03: posted Downstream Processing of Plasmid DNA for Gene Therapy and Genetic Vaccination

• 12:03: posted BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals.

• 14:14: posted FTA liver impressions as DNA template for detecting and genotyping fowl adenovirus.

• 10:54: posted Automated forensic DNA purification optimized for FTA card punches and identifiler STR-based PCR analysis.

• 17:07: posted Negative regulation of multifunctional Ca2+//calmodulin-dependent protein kinases: physiological and pharmacological significance of protein phosphatases
• 15:11: posted A photoreceptor-specific cadherin is essential for the structural integrity of the outer segment and for photoreceptor survival.
• 12:18: posted Chromosome Structural Proteins and RNA-Mediated Epigenetic Silencing
• 11:05: posted Incidence and clinical features of X-linked Cornelia de Lange syndrome due to SMC1L1 mutations.
• 10:52: posted Mutations in cohesin complex members SMC3 and SMC1A cause a mild variant of cornelia de Lange syndrome with predominant mental retardation.
• 10:48: posted RPGR-ORF15, which is mutated in retinitis pigmentosa, associates with SMC1, SMC3, and microtubule transport proteins.

• 12:02: posted Sons conceived by assisted reproduction techniques inherit deletions in the azoospermia factor (AZF) region of the Y chromosome and the DAZ gene copy number
• 12:02: posted Implantation-associated gene-1 (Iag-1): a novel gene involved in the early process of embryonic implantation in rat
• 12:01: posted Mental and psychomotor development of 2-year-old children born after preimplantation genetic diagnosis/screening
• 12:00: posted What next for preimplantation genetic screening (PGS)? Experience with blastocyst biopsy and testing for aneuploidy