Evolution of the genetic code. From the CG- to the CGUA-alphabet, from RNA double helix to DNA

by: Denis A Semenov

(5 May 2008)

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arXiv (abstract), arXiv (PDF)

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madhadron a 0 notes privées et 1 note publique sur cette article .

Doesn't make very much sense. Maybe if I read all the background literature he cites it would.

madhadron (note publique ) - 2008-05-07 08:56:50

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Résumé

A hypothesis of the evolution of the genetic code is proposed, the leading mechanism of which is the nucleotide spontaneous damage leading to AT-enrichment of the genome. The hypothesis accounts for stability of the genetic code towards point mutations, the presence of code dialects, emergence of stop codons, emergence of the DNA double helix and the symmetry of the genetic code table. The assumption of the originally triplet structure of the genetic code has been substantiated. A hypothesis concerning the primary structure of the first gene and the first protein has been proposed.

@misc{citeulike:2764238, abstract = {A hypothesis of the evolution of the genetic code is proposed, the leading mechanism of which is the nucleotide spontaneous damage leading to AT-enrichment of the genome. The hypothesis accounts for stability of the genetic code towards point mutations, the presence of code dialects, emergence of stop codons, emergence of the DNA double helix and the symmetry of the genetic code table. The assumption of the originally triplet structure of the genetic code has been substantiated. A hypothesis concerning the primary structure of the first gene and the first protein has been proposed.}, author = {Semenov, Denis A. }, citeulike-article-id = {2764238}, comment = {Doesn't make very much sense. Maybe if I read all the background literature he cites it would.}, eprint = {0805.0484}, keywords = {dna, evolution}, month = {May}, posted-at = {2008-05-07 08:56:50}, priority = {0}, title = {Evolution of the genetic code. From the CG- to the CGUA-alphabet, from RNA double helix to DNA}, url = {http://arxiv.org/abs/0805.0484}, year = {2008} }

RIS record

TY - ELEC ID - citeulike:2764238 L3 - citeulike-article-id:2764238 TI - Evolution of the genetic code. From the CG- to the CGUA-alphabet, from RNA double helix to DNA N2 - A hypothesis of the evolution of the genetic code is proposed, the leading mechanism of which is the nucleotide spontaneous damage leading to AT-enrichment of the genome. The hypothesis accounts for stability of the genetic code towards point mutations, the presence of code dialects, emergence of stop codons, emergence of the DNA double helix and the symmetry of the genetic code table. The assumption of the originally triplet structure of the genetic code has been substantiated. A hypothesis concerning the primary structure of the first gene and the first protein has been proposed. KW - dna KW - evolution N1 - Doesn't make very much sense. Maybe if I read all the background literature he cites it would. AU - Semenov, Denis PY - 2008/May/05/ UR - http://arxiv.org/abs/0805.0484 ER -

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